Eur. Phys. J. Appl. Phys.
Volume 56, Number 2, November 2011Topical Issue: 18th International Colloquium on Plasma Processes (CIP 2011)
|Number of page(s)||4|
|Published online||28 October 2011|
Biocompatibility of oxygen-plasma-treated polystyrene substrates
Jozef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia
2 Rudjer Boskovic Institute, Bijenička 54, 10000 Zagreb, Croatia
a e-mail: email@example.com
Revised: 12 July 2011
Accepted: 26 August 2011
Published online: 28 October 2011
The biocompatibility of polystyrene (PS) samples has been improved by treatment with weakly ionized highly non-equilibrium oxygen plasma. Samples were exposed to plasma for 30 s for which they have received a dose of ions of 4.5 × 1017 m−2 and a neutral oxygen atom dose of 3 × 10−23 m−2. Both untreated and plasma-treated samples were tested for biocompatibility according to the same procedure. Proliferation of human mammary epithelial cells (HMECs) on samples revealed a dramatically improved biocompatibility of polystyrene treated by oxygen plasma. The HMECs were deposited on all samples and incubated for 1, 2 and 6 days. MTT test revealed about two times higher activity of cell enzymes after 48 h incubation. The activity for plasma-treated samples remained much higher than for untreated samples even after 6 days of incubation when the samples were already covered with a dense film of HMECs.
© EDP Sciences, 2011
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.